Tech Notes

Motion Metric

Measurement of overall motion, as well as specific subtypes of activity such as circadian rhythms and particular aspects of locomotion, can be used as an integrated readout for tracking disease progression. Vium's platform enables motion tracking of subjects non-invasively and is used as a measure to track disease progression and treatment in a variety of animal models.

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PDF / 2 MB

Breathing Rate

Measuring changes in breathing rate can lead to the early detection of disease and is key in evaluating the safety profile of novel therapeutics. A range of conditions including exercise, stress, lung disorders, cardiovascular disease, metabolic acidosis, drug overdose, and central nervous system abnormalities can all manifest in detectable alterations in breathing rate.

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PDF / 0.7 MB

Arthritis Index™

The Vium Arthritis Index enables researchers to evaluate the efficacy and safety of therapeutic interventions in rodent models of RA through near realtime measurements and data analysis. Our use of physiological measurements combined with advanced analytics provides a highly sensitive readout of arthritis induction, as well as clinically relevant measures of therapeutic response.  

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PDF / 0.5 MB

Case Studies

Mouse Model of Liver Toxicity

We hypothesize that continuous monitoring of behavioral and physiological parameters will provide clinically relevant data to assess disease in induction rodent models, including the Con A- induced mouse model of liver disease. The objective of this study was to evaluate behavioral and physiological characteristics of Con A-induced mice using different doses of Con A.

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PDF / 0.8 MB

MRL/lpr Model of Systemic Lupus Erythematosus

We hypothesize that continuous monitoring of behavioral and physiological parameters will provide additional meaningful data to assess disease and efficacy in genetic rodent models of disease, including SLE. To address this hypothesis, the objectives of this study were: 1) To investigate behavioral and physiological characteristics of MRL/lpr mice using a low-touch, continuous monitoring platform, and 2) To evaluate and compare the effects of standard of care (SOC) compounds on conventional disease measures as well as behavioral and physiological phenotypes in MRL/lpr mice.

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PDF / 1.4 MB

Brochures

The Digital Vivarium

An overview of the Vium Digital Vivarium including our Smart Housing, Research Suite, and Discovery Lab Vivarium.

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PDF / 9.3 MB

Case Studies

Case studies on animal models run using the Vium Digital Vivarium

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PDF / 11.3 MB

Digital Metrics and Protocols

Overviews of our innovative Digital Metrics and example study protocols for research done using the Digital Vivarium

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PDF / 13.9 MB
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Scientific Posters

Digital Vivarium™ (PDF) 

Presented at the AALAS NCB Annual Symposium

Vium Smart Housing™ (PDF) 

Presented at the AALAS NCB Annual Symposium

MS Drug Efficacy Assessment (PDF)  

Presented at Neuroscience 2016

Automated Disease Assessment (PDF)

Presented at World Preclinical Congress 2017

Videos

Learn more about some of the exciting developments at Vium and hear from our customers, advisors, and founders.


Introducing Vium
Animal Welfare at Vium
Preclinical Research
Event Videos